The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance

Cell Metabolism

2015

Study summary

MOTS-c was examined in models of obesity and insulin resistance as a mitochondrial signaling peptide.

Peptides studied

Stack studied

Metabolic Stack

Key findings

MOTS-c improved insulin sensitivity and reduced obesity-related metabolic dysfunction in mice.

Study details

Study type

preclinical study

Journal

Cell Metabolism

DOI / PubMed

10.1016/j.cmet.2015.02.009

Year

2015

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Explore the science. Follow the connections.

Start with a peptide, a goal, a mechanism, or a study. Discover how every piece of research connects across the platform.

Search peptides, goals, studies,...

Research made connected. Build for curious minds.

© 2026 All rights reserved

This platform is for informational and research purposes only. It does not provide medical advice. Always consult a qualified healthcare provider.