Tirzepatide as compared with semaglutide for treatment of obesity
New England Journal of Medicine
2025
Study summary
Head-to-head trial comparing tirzepatide and semaglutide for obesity treatment.
Peptides studied
Goals studied
Stack studied
Advanced Metabolic Stack
Metabolic Stack
Key findings
Tirzepatide was superior to semaglutide for reduction in body weight and waist circumference at week 72.
Study details
Study type
randomized clinical trial
Journal
New England Journal of Medicine
DOI / PubMed
10.1056/NEJMoa2504186
Year
2025
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